RESUMO
Chronic myeloid leukemia is a myeloproliferative disorder caused by a clonal disturbance of the trunk cell and the accumulation of granulocytic series in the marrow, blood and other organs. We report a 63 years old male, carrier of a chronic myeloid leukemia whose clinical condition was complicated by the appearance of a T cell lymphoma. He was subjected to chemotherapy, that reduced the size of adenopathies and improved his general condition. Further studies are required to determine if there is a relationship between these two clinical entities
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Linfoma não Hodgkin/complicações , Leucemia Mielogênica Crônica BCR-ABL Positiva/complicações , Esplenomegalia/diagnóstico , Esplenomegalia/tratamento farmacológico , Linfoma não Hodgkin/diagnóstico , Linfoma não Hodgkin/tratamento farmacológico , Bussulfano/uso terapêutico , Leucemia Mielogênica Crônica BCR-ABL Positiva/diagnósticoRESUMO
Se presenta una experiencia de tratamiento con clozapina en 11 pacientes esquizofrénicos resistentes. Se discute la eficacia del tratamiento y sus efectos adversos, así como la metodología empleada
Assuntos
Humanos , Adulto , Esquizofrenia/tratamento farmacológico , Clozapina/farmacologia , Estudos Prospectivos , Resultado do Tratamento , Clozapina/administração & dosagem , Clozapina/efeitos adversosRESUMO
We report a boy in whom an advanced Hodgkin's disease, nodular sclerosis variety was diagnosed at 5 yeras of age and treated with exclusive chemotherapy. After 16 years of remission, he presented with a relapsed of the disease with a different histological pattern and was subjected to chemotherapy (C-MOPP/AVB) and unilateral axillary irradiation, obtaining a complete remission of the disease. Four months later, the patients is asymptomatic and without evidences of relapse